TABLE 4.
Antifungal | CLSI method |
EUCAST method |
EUCAST method at 30°C with shaking |
EUCAST method at 30°C |
YNB shaken |
YNB static |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
GM | Min-max | GM | Min-max | GM | Min-max | GM | Min-max | GM | Min-max | GM | Min-max | |
AmB | 0.72 | 0.12-16 | 1.03 | 0.25-32 | 0.90 | 0.12-32 | ND | ND | 0.95 | 0.25-8 | 1.15 | 0.12-32 |
Flucytosine | 2.9 | 0.12->64 | 4.51 | 0.12->64 | 8.59 | 0.12->64 | ND | ND | 2.44 | 0.12->64 | 2.93 | 0.12->64 |
Fluconazole | 8.2 | 0.50->64 | 8.00 | 0.25->64 | 9.75 | 0.25->64 | ND | ND | 6.03 | 0.25->64 | 10.61 | 0.25->64 |
Itraconazole | 0.47 | 0.03->8 | 0.41 | 0.015-32 | 0.47 | 0.015-16 | ND | ND | 0.27 | 0.015-16 | 0.31 | 0.015-16 |
Voriconazole | 0.28 | 0.015-8 | 0.26 | 0.015-16 | 0.33 | 0.015-16 | ND | ND | 0.12 | 0.015-2 | 0.17 | 0.015-8 |
Posaconazole | 0.6 | 0.12->8 | 0.56 | 0.03-16 | 0.49 | 0.015-16 | ND | ND | 0.24 | 0.03-2 | 0.22 | 0.015-16 |
Caspofungin | 12.4 | 2-16 | 13.37 | 2->16 | 9.74 | 0.03->16 | ND | ND | 9.33 | 1->16 | 10.34 | 1->16 |
Micafungin | >16 | 1->16 | >16 | 1->16 | 15.98 | 0.12->16 | ND | ND | 10.33 | 0.06->16 | 10.31 | 0.06->16 |
Anidulafungin | 13.7 | 1->16 | 13.72 | 0.50->16 | 10.75 | 0.03->16 | ND | ND | 6.01 | 0.03->16 | 5.27 | 0.03->16 |
GM, geometric mean; ND, not determined.