TABLE 2.

Structure of PFA and its in vitro antifungal activity compared to that of AMB

a Broth microdilution assays were performed according to CLSI guidelines. RPMI, RPMI 1640 medium; SBD, Sabourand dextrose broth.

b IC₅₀, concentration that results in 50% growth inhibition relative to that of the controls. MIC, the lowest concentration that allows no detectable growth. MFC, minimum fungicidal concentration, i.e., the lowest concentration that kills 100% of the cells. The data are in μg/ml and are average values from duplicate experiments.