TABLE 3.
Changes in S. aureus razupenem population profiles at 24 h and 48 h for MRSA strains
| Time (h) | fT>MIC range (%) | Growth on: |
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|---|---|---|---|---|---|---|---|
| 2× MIC recovery plates |
4× MIC recovery plates |
8× MIC recovery plates |
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| No. (%) of expts with >2-log-unit growth/total | Viable count (log CFU/ml), mean ± SD | No. (%) of expts with >2-log-unit growth/total | Viable count (log CFU/ml), mean ± SD | No. (%) of expts with >2-log-unit growth/total | Viable count (log CFU/ml), mean ± SD | ||
| 24 | 0.5-2.5 | 5/6 (83) | 4.3 ± 0.8 | 0/6 | <2 | 0/6 | <2 |
| >2.5-5.0 | 5/6 (83) | 4.8 ± 0.8 | 0/6 | <2 | 0/6 | <2 | |
| >5-10 | 3/5 (60) | 4.1 ± 0.6 | 0/5 | <2 | 0/5 | <2 | |
| >10-15 | 2/6 (33) | 3.4 | 0/6 | <2 | 0/6 | <2 | |
| >15-35 | 3/7 (43) | 3.2 ± 0.2 | 0/7 | <2 | 0/7 | <2 | |
| >35-70 | 0/9 | <2 | 0/9 | <2 | 0/9 | <2 | |
| >70 | 0/6 | <2 | 0/6 | <2 | 0/6 | <2 | |
| 48 | 0.5-2.5 | 6/6 (100) | 6.2 ± 1.3 | 3/6 (50) | 5.2 ± 1.4 | 1/6 (17) | 2.4 |
| >2.5-5.0 | 5/6 (83) | 7.1 ± 0.4 | 3/6 (50) | 5.3 ± 2.0 | 1/6 (17) | 6.5 | |
| >5-10 | 5/5 (100) | 5.0 ± 2.0 | 2/5 (40) | 3.8 | 0/6 | <2 | |
| >10-15 | 3/6 (50) | 4.4 ± 1.7 | 3/6 (50) | 4.3 ± 1.7 | 1/6 (17) | 2.4 | |
| >15-35 | 3/7 (43) | 3.7 ± 1.0 | 3/7 (43) | 3.7 ± 1.2 | 0/6 | <2 | |
| >35-70 | 1/9 (11) | 2.1 | 0/9 | <2 | 0/9 | <2 | |
| >70 | 0/6 | <2 | 0/6 | <2 | 0/9 | <2 | |