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. 2010 Dec 17;77(4):1335–1343. doi: 10.1128/AEM.01820-10

TABLE 6.

Results obtained in reversion studya

Group Dose (no. of CFU/mouse) Study day Wt gain (g)b Stomach wt (g)d No. of animals with increase in following characteristic/total no. animals per group:
No. of DNA copies of H. pylori/stomachd Total no. of ulcers/stomach H. pylori pathogenicity ratioc,d
Peyer's patches Spleen wt Mesenteric ganglion wt
A Placebo 14 −0.90 ± 0.60 0.174 ± 0.035 D 4/5 1/5 1/5 2.1 × 106 ± 1.9 × 106 F 1.00 ± 0.71 0.85 ± 0.90 H
21 0.06 ± 0.45 0.132 ± 0.032 D 5/5 0/5 1/5 3.6 × 107 ± 6.0 × 107 F 0.60 ± 0.89 0.02 ± 0.03 H
B 1 × 109 14 −0.36 ± 0.76 0.166 ± 0.038 E 2/5 0/5 0/5 4.4 × 106 ± 3.5 × 106 G 0.60 ± 0.55 0.13 ± 0.14 I
21 −0.20 ± 0.37 0.132 ± 0.013 E 2/5 0/5 0/5 4.9 × 107 ± 3.0 × 107 G 0.00 ± 0.00 0.00 ± 0.00 I
a

Data are the means ± standard deviations of the means (n = 5).

b

Body weight gain is expressed as final weight minus initial weight.

c

H. pylori pathogenicity ratio is expressed as total number of ulcers per million copies of H. pylori DNA in the stomach.

d

Pairs of values sharing the same capital letter are significantly different (P < 0.05).