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. 2011 Jan 12;18(3):393–405. doi: 10.1128/CVI.00359-10

FIG. 1.

FIG. 1.

Secretion of IFN-γ (ng/ml) by PBMCs isolated from control noninfected calves (⧫) and calves infected with Mycobacterium avium subsp. paratuberculosis by the following methods: oral (▪), intraperitoneal (▴), oral with dexamethasone administration (○), and oral with mucosal scrapings from a cow with clinical disease (✳). IFN-γ secretion during the 12-month study was measured in nonstimulated PBMCs (A), PBMCs stimulated with ConA (B), and PBMCs stimulated with a whole-cell sonicate of Mycobacterium avium subsp. paratuberculosis (MPS) (C). Data are expressed as means ± SEM. Significant differences between control and infection groups within given time points are represented by asterisks (**, P < 0.01; *, P < 0.05).