Percentages of IL-10+ T cells among PBMCs isolated from control noninfected calves and calves infected with Mycobacterium avium subsp. paratuberculosis by the following methods: oral, intraperitoneal, oral with dexamethasone administration, and oral with mucosal scrapings from a cow with clinical disease. Percentages of IL-10+ T cells were measured at 12 months within CD4, CD8, and γδ T-cell subpopulations stimulated with a whole-cell sonicate of Mycobacterium avium subsp. paratuberculosis (MPS). Data are expressed as means ± SEM. Significant differences between control and infection groups within given time points are represented by asterisks (*, P < 0.05).