Table 1.
Summary of shortening and lengthening events associated with the long Bcl telomere
| Parent colonya | No. of TRD events |
No. of elongation events |
Total no. of subclones examined | ||
|---|---|---|---|---|---|
| All of sampleb | Subset of samplec | All of sampled | Subset of samplee | ||
| 1 | 3 | 0 | 0 | 1 | 57 |
| 2 | 0 | 0 | 0 | 0 | 40 |
| 3 | 38 | 1 | 0 | 1 | 98 |
| 4 | 12 | 3 | 1 | 12 | 99 |
| 5 | 4 | 1 | 1 | 4 | 125 |
| 6 | 0 | 0 | 0 | 0 | 10 |
| 7 | 0 | 1 | 1 | 0 | 10 |
| 8 | 1 | 0 | 0 | 0 | 10 |
| 9 | 1 | 0 | 0 | 0 | 10 |
| 10 | 1 | 0 | 0 | 0 | 10 |
| 11 | 1 | 0 | 0 | 2 | 10 |
| 12 | 0 | 0 | 0 | 1 | 10 |
| 13 | 0 | 0 | 0 | 0 | 10 |
| 14 | 1 | 0 | 0 | 0 | 9 |
| 15 | 0 | 0 | 0 | 0 | 10 |
| Total | 62 | 6 | 3 | 21 | 518 |
The parent colonies were taken from 15 subclones of the long telomere transformant.
TRD events where telomere shortening occurred in all cells of the colony examined. This was indicated by the loss of the original long telomere band.
TRD events where telomere shortening occurred in only a percentage of the cells of the colony examined. This was indicated by the retention of a signal at the position of the original long telomere band.
Telomere elongation events where telomere elongation occurred in all cells of the colony examined.
Telomere elongation events where telomere elongation occurred in only a percentage of the colony examined, as indicated by retention of some signal at the position of the original Bcl telomere.