TABLE 2.
Inhibitory spectrum of S. mutans UA159
| Species (indicator strain[s])b | Group | Zone of inhibition diam (mm)a |
|||
|---|---|---|---|---|---|
| Wild type | Strain carrying: |
||||
| ΔnlmAB | ΔnlmC | ΔnlmABC | |||
| S. uberis (UT387) | Pyogenic | 22 ± 2 | — | 22 ± 2 | — |
| S. agalactiae (NEM306) | Pyogenic | 16 ± 1 | — | 13 ± 1 | — |
| S. iniae (K388) | Pyogenic | 14 ± 1 | 13 ± 1 | 9 ± 1 | 5 ± 0.5 |
| S. pyogenes (JRS4, AM3, K56) | Pyogenic | 24 ± 1 | 14 ± 1 | 17 ± 1 | 10 ± 1 |
| S. anginosus (CI) | Anginosus | 23 ± 1 | 16 ± 1 | 17 ± 1 | 5 ± 0.5 |
| S. constellatus (CI) | Anginosus | 25 ± 2 | — | 17 ± 1 | — |
| S. cristatus (ATCC 51100) | Mitis | 14 ± 1 | 4 ± 0.5 | 11 ± 1 | 4 ± 0.5 |
| S. gordonii (DL-1, ATCC 10558, M5) | Mitis | 17 ± 1 | — | 17 ± 1 | — |
| S. pneumoniae (ATCC 6303) | Mitis | 10 ± 1 | 10 ± 1 | 10 ± 1 | 10 ± 1 |
| S. sanguinis (SK36) | Mitis | 10 ± 1 | — | 9 ± 1 | — |
| S. salivarius (ATCC 25975) | Salivarius | 8 ± 1 | — | 8 ± 1 | — |
| S. bovis (TX20005) | Bovis | 9 ± 1 | 4 ± 0.5 | — | — |
| S. downei (ATCC 33798) | Mutans | — | — | — | — |
| S. sobrinus(6715) | Mutans | — | — | — | — |
| S. criceti(AHT) | Mutans | — | — | — | — |
| S. mutans (UA159, UA130, GS-5) | Mutans | — | — | — | — |
| S. ratti(BHT) | Mutans | — | — | — | — |
—, none or a <4-mm zone of inhibition. Values are means ± standard deviations resulting from at least three independent experiments performed in duplicates.
Three different strains for three streptococci were tested, as indicated. CI, clinical isolates.