TABLE 2.

Parameter values and model goodness of fit for models based on individual organ data

Organ	Model	Parameter valuesa				Model goodness of fit
						Including strain		Excluding strain
		ID50	c	a	b	Deviance (dofb)	P value	Deviance (dof)	P value
Liver	Beta Poisson	7.68	−1.22	0.33	1	11.2 (5)	0.05	17.4 (6)	0.01
	Log-logistic	7.83	−1.25	1	0.64	11.8 (5)	0.04	18.6 (6)	0.004
Spleen	Exponential	8.54	−1.26			6.2 (6)	0.40	22.0 (7)	0.003
	Log-logistic	8.59	−1.33	1	1.04	7.6 (5)	0.18	18.4 (6)	0.005
Mesenteric lymph	Beta Poisson	8.10	−1.19	0.40	1	11 (5)	0.05	16.2 (6)	0.01
node	Log-logistic	8.25	−1.24	1	0.69	9.6 (5)	0.09	16.2 (6)	0.01
Ileum	Beta Poisson	8.91	−1.36	0.96	1	2.4 (5)	0.79	12.4 (6)	0.05
	Log-logistic	8.87	−1.34	1	1.06	2.6 (5)	0.76	11.8 (6)	0.07

^aID₅₀, median infectious dose for the strain carrying an inlA PMSC mutation (CSUFSL N1-040); c, shift in ID₅₀ for the outbreak-associated epidemic clone strain (CSUFSL N1-054) relative to CSUFSL N1-040; a, intercept of the dose-response curve; b, slope of the dose-response curve.

^bdof, degrees of freedom.