TABLE 2.
Detection results for eight chemicals with DIER and YES bioassaysa
Strain | Chemical | Limit of detection (g/liter) | Linear scope (g/liter) | Relative estrogenic activity | Estradiol equivalency factor | Estrogenic activity |
---|---|---|---|---|---|---|
DIER | 17-β-Estradiol | 10−10 | 10−10-10−1 | 1.0 | 1.0 | Strong |
BPA | 10−10 | 10−10-10−2 | 10−4 | 1.2 × 10−4 | Strong | |
Chrysene | 10−7 | 10−6-10−1 | 10−4 | 0.98 × 10−4 | Moderate | |
6-OH-chrysene | 10−6 | 10−6-10−1 | 10−5 | 1.4 × 10−5 | Moderate | |
Benz[a]anthracene | NDb | ND | ND | ND | Weak | |
Pyrene | ND | ND | ND | ND | Weak | |
Progesterone | ND | ND | ND | ND | No | |
Testosterone | ND | ND | ND | ND | No | |
BJ3505 | 17-β-Estradiol | 10−10 | 10−10-10−1 | 1.0 | 1.0 | Strong |
BPA | 10−10 | 10−10-10−1 | 10−4 | 1.7 × 10−4 | Strong | |
Chrysene | 10−6 | 10−5-10−1 | 10−4 | 1.13 × 10−4 | Moderate | |
6-OH-chrysene | 10−6 | 10−6-10−2 | 10−5 | 1.1 × 10−5 | Moderate | |
Benz[a]anthracene | ND | ND | ND | ND | Weak | |
Pyrene | ND | ND | ND | ND | Weak | |
Progesterone | ND | ND | ND | ND | No | |
Testosterone | ND | ND | ND | ND | No |
Values represent data from seven separate experiments.
ND, not detected (when relative β-galactosidase activity is lower than 0.1).