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. 2010 Dec 13;79(3):1349–1362. doi: 10.1128/IAI.00984-10

FIG. 6.

FIG. 6.

il17ra−/− mice do not exhibit enhanced genital tract pathology during C. muridarum genital infection. Genital tract tissues were removed en bloc from C. muridarum-infected mice at 35 and 56 days postinfection (n = 5 mice per strain per time point). Tissues were scored for oviduct dilatation (A) and uterine horn distension (B). Scores for individual mice on day 35 (D35) and scores for day 56 (D56) are indicated. The median scores are indicated by dark lines. No differences in median pathology scores were noted between groups on either day examined (Mann-Whitney U test). Tissues were also examined grossly and histologically. Oviducts from C57BL/6 (C) and il17ra−/− (D) mice displayed similar inflammatory scores and oviduct dilatation. Uterine horns from C57BL/6 (E) and il17ra−/− (F) mice exhibited no significant differences in inflammation or fibrosis. The tissues were representative samples of the oviducts (C and D; magnification, ×40) and uterine horns (E and F; magnification, ×40) from C57BL/6 mice and il17ra−/− mice on day 56 postinfection.