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. 2011 Jan 31;79(4):1660–1670. doi: 10.1128/IAI.00872-10

TABLE 3.

ET bioassay results

Time (h) No. of mice (n = 5/group) with result after injection witha:
TY825 (wild type)
etb mutant
saeR mutant
arlR mutant
agrC mutant
sigB mutant
sarA mutant
sarS mutant
Activity Death Activity Death Activity Death Activity Death Activity Death Activity Death Activity Death Activity Death
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
4 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
5 0 0 0 0 0 0 0 0 0 0 0 1 4 0 0 0
6 0 0 0 0 0 0 0 0 0 0 1 2 5 0 0 2
7 0 1 0 2 0 0 0 0 0 0 2 3 5 0 1 5
8 0 3 0 2 0 0 0 2 0 0 2 3 5 0 1 5
a

Aliquots of bacterial cell suspension (108 bacteria ml−1) were administered subcutaneously to groups of 2-day-old ICR neonatal mice, and the occurrence of Nikolsky's sign (exfoliation activity) was monitored.