FIG. 6.
Activation of the LXR signaling pathway promotes bacterial replication. Prestimulation with RXR (9-cRA) and LXR (T091317) ligands or with 25-HC for 24 h did not alter the course of infection of RAW264 macrophage-like cells that lack LXRα. On the other hand, pretreatment with the same agonists of ZBM2 cells (B) or BMMs (C) increases the number of recovered live bacteria 12 h postinfection (MOI, 5).