Schematic summary of metabolic strategies in V. paradoxus S110. The depicted pathways were predicted based on the genomic data of V. paradoxus S110 analyzed by the JGI and KRIBB. Details are available in Fig. S1 in the supplemental material. The figure demonstrates integration of a range of anabolic and carbolic metabolisms, along with membrane-bound transport systems. These include the assimilation of carbon, nitrogen, and sulfur compounds and the degradation and subsequent utilization of xenobiotic contaminants in correlation with the central pathways that are recognized to operate in this microorganism. Individual pathways are denoted by single-headed arrows, while reversible pathways are denoted by double-headed arrows. Abbreviations: cw, clockwise (for oxidative TCA cycle); ccw, counter-clockwise (for reductive TCA cycle); AHL, acyl homoserine lactone; GA3P, glyceraldehyde-3-phosphate; G6P, glucose-6-phosphate; MTHF, 5,10-methylenetetrahydrofolate; PHB, polyhydroxy butyrate; APS, adenylyl sulfate; PAPS, 3-phosphoadenylyl sulfate; TTDP, thioether 3,3-thiodipropionic acid.