Metabolic responses of B. cereus strains F4430/73, F4810/72, F837/76, and PA. (A) Pathways for the excretion of partially oxidized metabolites. The reactions are represented by the names of the corresponding genes, as follows: ldhA, ldhB, and ldhC, l-lactate dehydrogenase; pfl, pyruvate formate lyase; pdh, pyruvate dehydrogenase; pta, phosphotransacetylase; ack, acetate kinase; adhE, acetaldehyde dehydrogenase; adhA, alcohol dehydrogenase; mdh, malate dehydrogenase; sdh, succinate dehydrogenase; citB, aconitase hydratase; citZ, citrate synthase. Reactions that normally function during aerobiosis are represented by gray arrows, and reactions that normally function during anaerobiosis are represented by black arrows. CIT, citrate; ICT, isocitrate; AKG, α-ketoglutarate; SUC, succinate; FUM, fumarate; MAL, malate; OAA, oxaloacetate; TCA, tricarboxylic acid cycle. (B) Extracellular metabolite analyses. (C) Specific Nhe production. Error bars indicate the standard errors of the means.