Table 5.
Resolution of all AHPV assay and HC2 test discordant specimensa
| Result | Histology | No. of samples | HPV type as determined by LA (no. of samples)**** |
||
|---|---|---|---|---|---|
| Negative | Low risk | High risk | |||
| AHPV−/HC2+ | Negative | 16 | 1 | 9 | 6 |
| CIN1 | 11 | 1 | 8 | 2 | |
| CIN2 | 7* | 1 | 4 | 1 | |
| CIN3 | 1*** | 1 | |||
| Cervical | 1 | 1** | |||
| Carcinoma | |||||
| AHPV+/HC2− | Negative | 1 | 1 | ||
| CIN1 | 2 | 2 | |||
| CIN2 | 4 | 4 | |||
| CIN3 | 4 | 4 | |||
| Cervical | 2 | 1 | 1 | ||
| Carcinoma | |||||
a
*, one could not be typed due to low sample volume; **, HPV 53; ***, microfocal CIN3 in conus; ****, high-risk determination is based on types detected in respective assays as high risk. HPV 66 was counted as high risk for the AHVP assay and as low risk for the HC2 test.