Assessment of gains from each two-step strategy for all 107 Enterobacteriaceae isolates (panels 1 and 2) and only the group 1 and 2 Enterobacteriaceae (panels 3 and 4) by using likelihood ratio graphs. Symbols: ×, the result with the first routine test, i.e., double-disk synergy test for graphs 1 and 3 or Vitek2 for graphs 2 and 4; ●, double-disk synergy test on MH agar; ○, double-disk synergy test on MH agar plus cloxacillin; ■, ESBL Etest on MH agar; □, ESBL Etest on MH agar plus cloxacillin; ◆, combined disk on MH agar; ◇, combined disk on MH agar plus cloxacillin; ▴, Cica-Beta test.