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. 2011 Mar;49(3):932–940. doi: 10.1128/JCM.02271-10

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Copyright © 2011, American Society for Microbiology.

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Fig. 3. — Dual T_m profiles of wild-type and QRDR mutant DNA. The T_m profiles of SMB QDR1 and QDR2 are shown in the presence of wild-type clinical M. tuberculosis DNA and various clinical QRDR mutants. The dual T_m peaks (°C) of each profile are listed in parentheses. (A) Wild-type gyrA(95T) (64.6 and 63.2); (B) wild-type gyrA(95S) (61.5 and 61.4); (C) G88A gyrA(95T) mutant (60.8 and 57.3); (D) A90V gyrA(95T) mutant (68.3 and 65.4); (E) A90V gyrA(95S) mutant (65.5 and 65.4); (F) S91P gyrA(95T) mutant (58.8 and 58.6); (G) D94A gyrA(95T) mutant (64.2 and 58.6); (H) D94G gyrA(95T) mutant (68.3 and 60.6); and (I) D94N gyrA(95T) mutant (62.9 and 57.4).