Table 3.
MICs of antimicrobials against isolates of P. aeruginosa, including 39016a
| Antimicrobial | MIC for isolate 39016 | Value for all isolates, including 39016 |
P. aeruginosa systemic breakpoint | |||
|---|---|---|---|---|---|---|
| MIC50 | MIC90 | Min | Max | |||
| Penicillin | 256 | 512 | 512 | 256 | 512 | NA |
| Cefuroxime | 256 | 300 | 512 | 256 | 512 | NA |
| Ceftazidime | 1.5 | 1 | 1.50 | 0.25 | 3 | 8 |
| Chloramphenicol | 24 | 512 | 512 | 0.09 | 512 | NA |
| Gentamicin | 1.5 | 1.50 | 2 | 0.19 | 12 | 4 |
| Amikacin | 2 | 2 | 3 | 1 | 512 | 8 |
| Vancomycin | 256 | 512 | 512 | 256 | 512 | NA |
| Teicoplanin | 256 | 512 | 512 | 256 | 512 | NA |
| Ciprofloxacin | 0.94 | 0.09 | 0.25 | 0.03 | 1 | 0.5 |
| Ofloxacin | 0.75 | 0.50 | 1.50 | 0.03 | 6 | 2 |
All values are in mg/liter. The table shows the minimum (Min) and maximum (Max) MICs and the MIC at which 50% (MIC50) and 90% (MIC90) of isolates were inhibited for a collection of keratitis isolates reported previously (24, 51). The systemic breakpoint concentrations for which P. aeruginosa is regarded as susceptible or resistant to that antimicrobial according to the British Society of Antimicrobial Chemotherapy (1) are included. NA, not applicable.