Table 2.
Parameter | Identification of MTC in BACTEC cultures based on: |
|||
---|---|---|---|---|
Serpentine cording in smear | Positivity in ESAT-6/CFP-10 ICA | Intersection of serpentine cording in smear and positivity in ESAT-6/CFP-10 ICAc | Union of serpentine cording in smear and positivity in ESAT-6/CFP-10 ICAd | |
% Sensitivity | 92.5 | 97 | 90.4 | 99.1 |
% Specificity | 97.4 | 97.4 | 100 | 94.8 |
% PPV | 97.8 | 97.9 | 100 | 95.9 |
% NPV | 91.4 | 96.4 | 89.4 | 98.9 |
Likelihood ratiob | 35.6 | 37.3 | INe | 19.1 |
The data are from identifications of MTC in the 603 BACTEC cultures shown in Table 1.
Likelihood ratio = sensitivity/(1 − specificity).
This indicates that both serpentine cording in smear and positivity in the ESAT-6/CFP-10 ICA were required in order to identify the culture to contain MTC.
This means that either serpentine cording in smear, positivity in the ESAT-6/CFP-10 ICA, or a combination of both alone was sufficient in order to identify the culture to contain MTC.
IN, infinite.