TABLE 1.
Conservation of V1 loop residue 153
| Clade or CRF | Prevalence (%)a at amino acid: |
Total no. of sequences | |
|---|---|---|---|
| E153 | G153 | ||
| Clades | |||
| A | 74.22 | 10.59 | 1,699 |
| B | 89.40 | 3.86 | 17,721 |
| C | 79.55 | 3.42 | 4,968 |
| D | 12.43 | 23.98 | 1,593 |
| G | 22.38 | 1.23 | 648 |
| CRF | |||
| CRF01_AE | 32.92 | 2.97 | 1,953 |
| CRF02_AG | 33.84 | 28.24 | 1,179 |
a
Residue E153 is conserved across clades. V1 sequences were obtained from the HIV database (http://www.hiv.lanl.gov/content/index) for clades A, B, C, D, G, AE, and 02AG. These sequences were aligned using CLUSTAL W2 and manually corrected. E153 is highly conserved across clades A, B, and C. G153 is most prevalent in clades D and 02AG.