TABLE 5.

Numbers of synonymous and nonsynonymous mutations within other than universally recognized immunodominant epitopes in responders and nonresponders before, during, and after therapy

Time	No. of mutationsa
	Synonymous		Nonsynonymous
	R	NR	R	NR
TW0	5 (0-13)	5 (0-14)	2 (0-4)	2 (0-4)
TW9	6 (1-13)	6 (0-15)	2 (0-4)	2 (0-4)
TW28	6 (1-14)	6 (1-15)	2.5 (0-6)	2.5 (1-5)
TW52	6 (0-14)	6 (0-15)	2 (0-5)	2 (0-6)
FUW24	5.5 (1-13)	6 (0-14)	2 (0-6)	2 (1-5)

^aResults are expressed as median and range.