TABLE 5.
Comparison of viral load in nasal and oral swabs
| Route | Dose | Oral swabs |
Nasal swabs |
||||
|---|---|---|---|---|---|---|---|
| Mean peak virus titera (log10 PFU/ml) | Mean day of initial detection (range) | Mean day of peak virus titer (range) | Mean peak virus titer (log10 PFU/ml) | Mean day of initial detection (range) | Mean day of peak virus titer (range) | ||
| i.v. | 5 × 107 | 4.4 (3.3-5.1) | 4.5 (2-7) | 9.0 (5-12) | 5.6 (4.6-6.0) | 4.8 (4-6) | 8.8 (5-12) |
| 5 × 106 | 5.0 (3.0-5.7) | 5.2 (4-7) | 9.6 (6-14) | 5.1 (3.3-5.9) | 8.2 (7-10) | 12.5 (8-21) | |
| i.b. | 5 × 106 | 4.2 (3.0-4.4) | 7.0 (5-9) | 12.0 (11-14) | 5.4 (5.3-5.5) | 9.7 (7-9) | 11.3 (9-14) |
| 5 × 105 | 2.4 (2.0-2.8) | 7.2 (5-9) | 9.5 (8-12) | 5.3 (3.3-5.9) | 6.8 (5-10) | 7.5 (5-12) | |
a
Viral load determined by the plaque assay of nasal and oral swabs on BSC-1 cells.