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. 2010 Dec 28;31(5):1054–1065. doi: 10.1128/MCB.00732-10

FIG. 2.

FIG. 2.

Akt activation in lung epithelium induces tachypnea and delayed maturation of the lung. (A) Body weight at P0 of control (Cont; n = 6) and DTG (n = 4) mice from 2 dams. (B) Respiratory rate at P0 of control (n = 14) and DTG (n = 8) mice from 4 dams. (C) Histological analysis. HE, PAS, and toluidine blue staining of lung sections at P0 and P2. Scale bar, 50 mm. (D) Aerated lung area in control and DTG mice at P0 and P2. *, P < 0.05 versus control. (E) Thickness of alveolar septum in control and DTG mice at P0 and P2. *, P < 0.05 versus control. For experiments shown in panels D and E, n = 3 from a single dam under all conditions.