TABLE 4.

Downregulation of genes involved in signal transduction and apoptosis in viruliferous whiteflies

Category or gene ID	Homologous functiona	Species	Accession no.	FCb
Toll-like signaling pathway
BT_B_ZJU_Singletons96892	Transmembrane trafficking protein	Tribolium castaneum	XP_971914.1	−9.5
BT_B_ZJU_Singletons24867	TRAF-type zinc finger containing 1	Xenopus tropicalis	XP_001943669.1	−3.4
BT_B_ZJU_Singletons101328	Leucine-rich transmembrane protein	Pediculus humanus corporis	XP_002422869.1	−1.3
MAPK pathway
BT_B_ZJU_Singletons103594	MAPKK4	Nasonia vitripennis	XP_001603456.1	1.9
BT_B_ZJU_Singletons101082	MAPKK1-interacting protein 1	Apis mellifera	XP_001121654.1	2.4
BT_B_ZJU_Singletons102809	Calcium-binding protein p22	Maconellicoccus hirsutus	ABM55600.1	−9.5
BT_B_ZJU_Singletons99736	MAPK activating protein	Apis mellifera	XP_624118.1	−4.4
BT_B_ZJU_Singletons98676	MAP-binding protein-interacting protein	Nasonia vitripennis	XP_001605487.1	−2.4
RIG-I-like receptor pathway
BT_B_ZJU_Singletons103928	DEAD box ATP-dependent RNA helicase	Acyrthosiphon pisum	XP_001951890.1	−1.7
Notch pathway
BT_B_ZJU_Singletons26945	Deltex	Pediculus humanus corporis	XM_002426000.1	−2.4
TGF-beta pathway
BT_B_ZJU_Singletons101016	DNA-binding protein inhibitor	Ixodes scapularis	XM_002414872.1	−2.9
Apoptosis
BT_Q_ZJU_Singletons13955	Apoptosis inhibitor	Pediculus humanus corporis	XP_002423394.1	8.9
BT_B_ZJU_Singletons11470	Programmed cell death protein 11	Acyrthosiphon pisum	XP_001951020.1	3.1
BT_Q_ZJU_Singletons27465	Cyclin B	Nasonia vitripennis	NP_001154932.1	−3.3
BT_B_ZJU_Singletons103804	Cyclin K	Pediculus humanus corporis	XP_002428532.1	−3.0
BT_B_ZJU_Singletons102809	Calcium-binding protein p22	Maconellicoccus hirsutus	ABM55600.1	−9.5
BT_B_ZJU_Singletons97698	Programmed cell death protein 2	Nasonia vitripennis	XP_001603635.1	−2.5
BT_B_ZJU_Singletons100224	Proliferating cell nuclear antigen	Fenneropenaeus chinensis	ABM66815.1	−3.1

^aThe function of the homologous gene.

^bFC, fold change (log₂ ratio) of gene expression.