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. 2011 Jan 26;85(7):3106–3119. doi: 10.1128/JVI.01456-10

FIG. 4.

FIG. 4.

Effect of compound 7 on the infectivity of HIV/EBOV-GP mutants. 293T cells were infected with mutant or wild-type HIV/EBOV-GP pseudotype virus in the presence of increasing concentrations of compound 7. Inhibition of HIV/EBOV-GP pseudotype infection was detected as a reduced luciferase signal. Error bars indicate standard deviations. (A) Effect of compound 7 on the infectivities of R64K, N69A, L70A, D78A, and K84A HIV/EBOV-GP mutants. (B) Effect of compound 7 on the infectivities of R172A, L184A, I185A, L186A, K190A/K191A, and Y225A HIV/EBOV-GP mutants.