FIG. 8.

Analysis of viral load in the liver, spleen, and lung tissues of RAG-1^−/− and C57BL/6 mice. Organs of RAG-1^−/− mice were collected when individual animals died due to infection, ranging from day 26 to day 32 p.i. for the group infected with ECTVΔN1L. The organs of control animals were removed at the end of the experiment (day 32 p.i.). C57BL/6 mice infected with the ECTV wt that succumbed to infection died between day 10 and day 14 p.i. All other C57BL/6 mice infected with the ECTV wt or ECTVΔN1L that did not die during the period of observation were sacrificed at the end of the experiment (day 32 p.i.), and organs were removed and homogenized. Viral titers were determined by plaque assays. c, control; ΔN1L, ECTVΔN1L; wt, ECTV wt.