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Limited impact of the codon 72 polymorphism of p53 on cancer incidence. (A) Kaplan-Meier analysis of survival data obtained from P72 and R72 mice crossed with Eμ-myc transgenic mice (C57BL/6 background). Statistical significance was assessed using the log rank test. (B) Kaplan-Meier analysis of survival data from P72 and R72 mice crossed with p53+/− mice to generate P/−, R/−, and +/− mice (C57BL/6 background). Statistical significance was assessed using the log rank test.
