TABLE 2.
Mutations within the mRAC subunitsa
| mRAC subunit | Name | Mutation(s) |
|---|---|---|
| MPP11 | MPP11-QPD | H119Q (inactivation of the J domain) |
| Hsp70L1 | L1-K68A | K68A (inactivation of the ATPase) |
| L1-E172A | E172A (inactivation of the ATPase) | |
| L1-LKA | G200L, T201K, S202A (affects γ-phosphate coordination) | |
| L1-ΔC | Amino acids 1-383 (deletion of the C-terminal domain) |
See Fig. 1A; also see Fig. S1 in the supplemental material.