Table 4.
HLA group | Vaccine arm |
Placebo arm |
||
Expected | Actual | Expected | Actual | |
Protective | 30% (22/73) | 44% (32/73) | 31% (11/37) | 16% (6/37) |
Neutral | 62% (45/73) | 49% (36/73) | 61% (23/37) | 73% (27/37) |
Unfavorable | 8% (6/73) | 7% (5/73) | 8% (3/37) | 11% (4/37) |
NOTE. Expected phenotypic frequencies based on A5197 ethnic distribution and calculated from HLA alleleic frequencies of U.S.-based cohorts of European Americans and African Americans (M. Carrington personal communication), and Hispanic and Asian Americans [1, 2].