Figure 5.

Antibody and T cell responses to 5 Burkholderia pseudoamallei proteins of healthy individuals vs recovered melioidosis patients. The plasma and blood samples collected from 26 recovered melioidosis patients and 15 healthy control participants were tested for antibodies to B. pseudomallei proteins by microarray and IFN-γ induction by whole-blood assay. Reactive results of antibody testing were defined as a signal antibody intensity higher than the mean + 2 standard deviations (SDs) of the “no DNA” control. The positive for IFN-γ induction was defined as IFN-γ higher than the mean + 2 SDs of medium controls. Ab⁺ and Ab^–, positive and negative for antibody response, respectively; T⁺ and T^–, positive and negative for T cell response by IFN-γ production, respectively.