Table 3.

pCR Rates by Disease Subtype, Receptor Status, Stage, and Treatment Arm

Variable	Standard Arm		Continuous Arm		Total		P†
	No.*	%	No.*	%	No.*	%
Overall							.45
pCR	37/179	20.7	43/177	24.3	80/356	22.5
No pCR or no surgery	142/179	79.3	134/177	75.7	276/356	77.5
Inflammatory breast cancer							.06
pCR	7/56	12.5	15/55	27.3	22/111	19.8
No pCR or no surgery	49/56	87.5	40/55	72.7	88/111	80.2
Locally advanced breast cancer							.88
pCR	30/123	24.4	28/122	23.0	58/245	23.7
No pCR or no surgery	93/123	75.6	94/122	77.0	187/245	76.3
Receptor-negative breast cancer							.40
pCR	25/86	29.0	26/73	35.6	51/159	32.1
No pCR or no surgery	61/86	71.0	47/73	64.4	108/159	67.9
Receptor-positive breast cancer							.39
pCR	9/84	10.7	15/98	15.3	24/182	13.2
No pCR or no surgery	75/84	89.3	83/98	84.7	158/182	86.8
Stage IIB							.23
pCR	13/35	37.1	4/21	19.1	17/56	30.4
No pCR or no surgery	22/35	62.9	17/21	80.9	39/56	59.6
Stage IIIA							.67
pCR	16/54	29.6	14/56	25.0	30/110	27.3
No pCR or no surgery	38/54	70.4	42/56	75.0	80/110	72.7
Stage IIIB							.0057
pCR	8/86	9.3	24/93	25.8	32/179	17.9
No pCR or no surgery	78/86	90.7	69/93	74.2	147/179	82.1

Abbreviation: pCR, pathologic complete response.

^*No. refers to No. achieving indicated result (pCR v no pCR) over total evaluated for this end point.

^†All P values are two sided.