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. 2011 Mar 30;6(3):e18085. doi: 10.1371/journal.pone.0018085

Figure 4. Influence of CR on inflammatory protein expressions in CT-2A astrocytoma.

Figure 4

Cyclooxygenase-2 (COX-2) (A) and Allograft Inflammatory Factor 1 (AIF-1) (B) in cytosolic extracts of the CT-2A astrocytoma. COX-2 and AIF-1 have both been reported to be downstream proinflammatory gene-product effectors of the activated NF-κB. The histograms illustrate the average relative expression of the indicated protein normalized to β-actin in CT-2A tumors (A-B). Values are expressed as normalized means ± S.E.M of 4–5 independent tissue samples/group. The asterisks indicate that the value is significantly different in the CR tumor than in the AL tumor at * P<0.05, † P<0.001 (Student t-test). Two representative samples are shown for each tissue type.