Table 2.
Genes downregulated and upregulated in podocytes treated with high glucose for two week compared to podocytes cultured in normal glucose conditions. A cut off of 3 fold changes was used to filter the data (see methods).
| probe set | Downregulated gene | Accession | fold change |
|---|---|---|---|
| 1427747_a_at | Lcn2: lipocalin 2 | X14607 | −7.03 |
| 1459713_s_at | Ano1: anoctamin 1, calcium activated chloride channel | AU040576 | −5.46 |
| 1434188_at | Slc16a12: solute carrier family 16 (monocarboxylic acid transporters), member 12 | AV220703 | −5.01 |
| 1419728_at | Cxcl5: chemokine (C-X-C motif) ligand 5 | NM_009141 | −4.49 |
| 1456078_x_at | Tubb2c /// Tubb2c-ps2: tubulin, beta 2C /// tubulin, beta 2c, pseudogene 2 | BB012080 | −4.32 |
| 1452014_a_at | Igf1: insulin-like growth factor 1 | AF440694 | −4.18 |
| 1423611_at | Alpl: alkaline phosphatase, liver/bone/kidney | AW319615 | −4 |
| 1435603_at | Sned1: sushi, nidogen and EGF-like domains 1 | BB487754 | −3.91 |
| 1458536_at | Ccni: Cyclin I | BB097972 | −3.69 |
| 1439364_a_at | Mmp2: matrix metallopeptidase 2 | BF147716 | −3.67 |
| 1448595_a_at | Bex1: brain expressed gene 1 | NM_009052 | −3.6 |
| 1454296_at | 4631402F24Rik: RIKEN cDNA 4631402F24 gene | AA739023 | −3.6 |
| 1450014_at | Cldn1: claudin 1 | NM_016674 | −3.5 |
| 1453550_a_at | Far1: fatty acyl CoA reductase 1 | AK011187 | −3.47 |
| 1449909_at | 2010005H15Rik: RIKEN cDNA 2010005H15 gene | NM_029733 | −3.44 |
| 1429951_at | Ssbp2: single-stranded DNA binding protein 2 | AK005150 | −3.36 |
| 1430097_at | 8430436C05Rik: RIKEN cDNA 8430436C05 gene | AU016566 | −3.35 |
| 1437405_a_at | Igfbp4: insulin-like growth factor binding protein 4 | BB787243 | −3.25 |
| 1459649_at | Mm.150125.1 | AI662750 | −3.23 |
| 1416441_at | Pgcp: plasma glutamate carboxypeptidase | BB468025 | −3.16 |
| 1440107_at | Mm.131403.1 | BB077622 | −3.15 |
| 1421239_at | Il6st: interleukin 6 signal transducer | AA717838 | −3.1 |
| 1429696_at | Gpr123: G protein-coupled receptor 123 | BE946247 | −3.1 |
| 1417625_s_at | Cxcr7: chemokine (C-X-C motif) receptor 7 | BC015254 | −3.09 |
| 1442254_at | Mm.207501.1 | BB366659 | −3.04 |
| probe set | Upregulated gene | Accession | fold change |
| 1455930_at | Mm.28870.2 | BI651113 | 13.95 |
| 1419063_at | Ugt8a: UDP galactosyltransferase 8A | NM_011674 | 5.26 |
| 1444199_at | Mm.45087.1 | AW046689 | 4.89 |
| 1431315_at | Hyls1: hydrolethalus syndrome 1 | BM570636 | 4.59 |
| 1449751_at | Slc6a6: Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | AA589629 | 4.57 |
| 1422944_a_at | Diap3: diaphanous homolog 3 (Drosophila) | NM_019670 | 4.46 |
| 1430786_at | 1110002E22Rik: RIKEN cDNA 1110002E22 gene | BE991102 | 4.39 |
| 1426278_at | Ifi27l2a: interferon, alpha-inducible protein 27 like 2A | AY090098 | 4.37 |
| 1427184_at | Tcrb-J: T-cell receptor beta, joining region | BF318536 | 3.97 |
| 1421262_at | Lipg: lipase, endothelial | BC020991 | 3.95 |
| 1422155_at | Hist2h3c2: histone cluster 2, H3c2 | BC015270 | 3.79 |
| 1455730_at | Dlgap5: discs, large (Drosophila) homolog-associated protein 5 | BM250919 | 3.67 |
| 1441757_at | 1190002F15Rik: RIKEN cDNA 1190002F15 gene | AI120476 | 3.65 |
| 1430419_at | 2310031A07Rik: RIKEN cDNA 2310031A07 gene | AK009549 | 3.64 |
| 1421350_a_at | Grip1: glutamate receptor interacting protein 1 | NM_130891 | 3.58 |
| 1439040_at | Cenpe: centromere protein E | BG068387 | 3.57 |
| 1447870_x_at | 1110002E22Rik: RIKEN cDNA 1110002E22 gene | BB099116 | 3.57 |
| 1440862_at | Mm.153468.1 | BB629079 | 3.44 |
| 1434847_at | Cnnm4: cyclin M4 | BB432741 | 3.31 |
| 1421754_at | AY036118: cDNA sequence AY036118 | NM_133243 | 3.3 |
| 1452458_s_at | Ppil5: peptidylprolyl isomerase (cyclophilin) like 5 | BC022648 | 3.28 |
| 1417587_at | Timeless: timeless homolog (Drosophila) | BM230269 | 3.26 |
| 1449171_at | Ttk: Ttk protein kinase | NM_009445 | 3.26 |
| 1439510_at | Sgol1: shugoshin-like 1 (S. pombe) | BB410537 | 3.25 |
| 1417019_a_at | Cdc6: cell division cycle 6 homolog (S. cerevisiae) | NM_011799 | 3.23 |
| 1417938_at | Rad51ap1: RAD51 associated protein 1 | BC003738 | 3.2 |
| 1452912_at | Dscc1: defective in sister chromatid cohesion 1 homolog (S. cerevisiae) | AK011162 | 3.17 |
| 1427004_at | Fbxo2: F-box protein 2 | BB311718 | 3.09 |
| 1440146_at | Vps13a: vacuolar protein sorting 13A (yeast) | BB829606 | 3.09 |
| 1420707_a_at | Traip: TRAF-interacting protein | AK012948 | 3.06 |
| 1421881_a_at | Elavl2: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | BB105998 | 3.06 |
| 1418480_at | Ppbp: pro-platelet basic protein | NM_023785 | 3 |