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Apparent pseudo-first order rate constants for inhibition of recombinant rat MAO A and MAO B activities by pargyline and by TEMPO-pargyline analogues for both MOM-bound and detergent-purified forms.
| k (inactivation)(s−1) | ||||
|---|---|---|---|---|
| Inhibitor | MAO A (Purified) | MAO A (MOM) | MAO B (Purified) | MAO B (MOM) |
| Pargyline | 9.4 ±1.1 | 44.8±6.2 | too fast to measure | too fast to measure |
| ParSL-1 | 1.1±0.1 | 1.62±0.06 | 4.0±0.6 | 4.8±0.8 |
| ParSL-2 | 0.3±0.02 | 0.15±0.04 | 3.8±0.2 | 4.1±0.3 |
| ParSL-3 | 4.0±0.2 | 6.3±0.9 | 0.6±0.06 | 0.54±0.24 |
