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. Author manuscript; available in PMC: 2012 Apr 5.
Published in final edited form as: Biochemistry. 2011 Mar 8;50(13):2691–2700. doi: 10.1021/bi2000966

FIGURE 6.

FIGURE 6

Fluorescence intensity maps at given times after injection of LS224 and LS296 (A) showing the disparate extravasation and kinetics of the compounds, ex/em 780/800 nm. Fluorescence values at different pixels for calculating kurtosis showed no significant change in the shape (B) for LS224 and therefore no changes in kurtosis (C) over 6 h while dramatic changes occurred in peak shape (D) and kurtosis (E) for LS296 within 3 h.