Environmental Actions on Somatic Cells |
Allows tissue specific toxicology and critical for adult onset disease in the individual exposed, but not capable of transmitting a transgenerational phenotype. |
Environmental Actions on Germ Cells |
Allows transmission between generations and in the absence of direct exposure promotes a transgenerational phenotype. |
Multigenerational Phenotypes |
Coincident direct exposure of multiple generations to an environmental factor or toxicant promoting a toxicology in the multiple generations exposed. |
Transgenerational Phenotypes |
After the initial exposure, the transgenerational phenotype is transmitted through the germ line in the absence of direct exposure. |
Epigenetics |
Molecular factors and processes around the DNA that regulate genome activity that are independent of DNA sequence and are mitotically stable. |