Table 7.

Techniques for Measuring DNA Methylation and Epigenome

CATEGORY	TECHNICAL BASIS	REFERENCES
Global Methylation	HPLC	[83]
	Radioactive Incorporation	[84]
	Antibody Labeling and Cytometry	[82]
Local Methylation	Restriction Enzyme Digestion	[85]
	Combined Restriction Enzyme and Bisulfite Conversion	[81]
	Bisulphite Conversion and Sequencing	[86, 87, 90]
	Bisulfite Conversion and Pyrosequencing	[88]
	Bisulfite Conversion and Mass Spectometry	[89]
Genome-wide Methylation	MeDIP - Chip	[56, 91]
	ChIP - Seq	[94]