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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Circ Cardiovasc Imaging. 2010 Jul 9;3(5):550–558. doi: 10.1161/CIRCIMAGING.109.918540

Figure 4. Serial histograms and histopathology.

Figure 4

On the top portion of the Figure, 4 week histograms of the number of pixels (y-axes) and intensities (x-axes) in individual animals after receipt of saline (top left), doxorubicin without (top middle) and with (top right) an ejection fraction (EF) drop. On the right are 40-power haematoxylin and eosin (H&E) histopatholigic images from the same animals. As shown, mean intensity increased in the animals that dropped their EF corresponding to vacuolization (arrows bottom right H&E).