Skip to main content
. 2001 Mar 13;98(6):3519–3524. doi: 10.1073/pnas.061449498

Figure 7.

Figure 7

NBTA protects cultured hippocampal neurons against NMDA receptor-mediated excitotoxic death. Trypan-blue exclusion assays of control neurons (A) and neurons exposed to 200 μM NMDA in the absence (B) or presence of 10 μM memantine (C) or 10 μM NBTA (D). (Scale bars = 3 μm.) (E) Neuronal death induced by NMDA in the absence and presence of 10 μM MK-801, 10 μM memantine, or 10 μM NBTA. (F) Neuronal death induced by kainate in the absence or presence of 20 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), 10 μM MK-801, 10 μM memantine, or 10 μM NBTA. Data are mean ± SEM, n = 2,000. ***, P < 0.01 for the difference when compared with the controls (NMDA- or kainate-treated groups).