Table 1. Childhood cancer diagnosed during 2003–2004 in residents of England, Wales and Scotland.
| Stratification factor |
Number of registrations (% of total) by source of notification
|
Capture-recapture estimates
|
||||||
|---|---|---|---|---|---|---|---|---|
| Total | CR only |
CCLG only
|
Number of cases
|
Completeness
|
||||
| CR feedback assumption: | A | B | A | B | A | B | ||
| Crude | 2985 | 206 (7%) | 224 (8%) | 117 (4%) | 3003.1 | 2994.1 | 99% | 100% |
| CR zone of residence | P(het)<0.001 | P(het)<0.001 | P(het)<0.001 | |||||
| Eastern | 293 | 24 (8%) | 29 (10%) | 28 (10%) | 295.9 | 295.8 | 99% | 99% |
| Mersey | 123 | 2 (2%) | 11 (9%) | 10 (8%) | 123.2 | 123.2 | 100% | 100% |
| North west | 218 | 11 (5%) | 13 (6%) | 9 (4%) | 218.7 | 218.5 | 100% | 100% |
| Northern/Yorkshire | 325 | 10 (3%) | 21 (6%) | 11 (3%) | 325.7 | 325.4 | 100% | 100% |
| Oxford | 157 | 8 (5%) | 4 (3%) | 1 (1%) | 157.2 | 157.1 | 100% | 100% |
| South West | 333 | 24 (7%) | 3 (1%) | 2 (1%) | 333.2 | 333.2 | 100% | 100% |
| Thames | 559 | 51 (9%) | 103 (18%) | 33 (6%) | 571.9 | 562.5 | 98% | 99% |
| Trent | 261 | 14 (5%) | 17 (7%) | 10 (4%) | 262.0 | 261.6 | 100% | 100% |
| West Midlands | 294 | 7 (2%) | 7 (2%) | 5 (2%) | 294.2 | 294.1 | 100% | 100% |
| Wales | 147 | 32 (22%) | 0 (0%) | 0 (0%) | 147.0 | 147.0 | 100% | 100% |
| Scotland | 275 | 23 (8%) | 16 (6%) | 8 (3%) | 276.6 | 275.8 | 99% | 100% |
| Stratified | 3005.7 | 2994.0 | 99% | 100% | ||||
| Age at diagnosis (years) | P(het)<0.001 | P(het)=0.012 | P(het)=0.325 | |||||
| Under 1 | 305 | 22 (7%) | 38 (12%) | 15 (5%) | 308.4 | 306.2 | 99% | 100% |
| 1–4 | 995 | 38 (4%) | 73 (7%) | 38 (4%) | 998.1 | 996.6 | 100% | 100% |
| 5–9 | 807 | 49 (6%) | 56 (7%) | 37 (5%) | 810.9 | 809.5 | 100% | 100% |
| 10–14 | 878 | 97 (11%) | 57 (6%) | 27 (3%) | 885.6 | 881.5 | 99% | 100% |
| Stratified | 3003.1 | 2993.8 | 99% | 100% | ||||
| Diagnostic group | P(het)<0.001 | P(het)=0.036 | P(het)=0.245 | |||||
| Leukaemia | 960 | 30 (3%) | 77 (8%) | 35 (4%) | 962.7 | 961.2 | 100% | 100% |
| Lymphoma | 271 | 16 (6%) | 22 (8%) | 10 (4%) | 272.5 | 271.7 | 99% | 100% |
| CNS tumours | 733 | 58 (8%) | 41 (6%) | 26 (4%) | 736.7 | 735.3 | 99% | 100% |
| Neuroblastoma | 185 | 6 (3%) | 17 (9%) | 7 (4%) | 185.6 | 185.2 | 100% | 100% |
| Retinoblastoma | 83 | 2 (2%) | 14 (17%) | 9 (11%) | 83.4 | 83.3 | 100% | 100% |
| Renal cancer | 172 | 3 (2%) | 14 (8%) | 8 (5%) | 172.3 | 172.2 | 100% | 100% |
| Hepatic cancer | 34 | 0 (0%) | 0 (0%) | 0 (0%) | 34.0 | 34.0 | 100% | 100% |
| Bone cancer | 132 | 9 (7%) | 11 (8%) | 8 (6%) | 132.9 | 132.6 | 99% | 100% |
| Soft-tissue sarcoma | 217 | 20 (9%) | 11 (5%) | 5 (2%) | 218.2 | 217.5 | 99% | 100% |
| Germ cell/gonadal | 98 | 14 (14%) | 12 (12%) | 6 (6%) | 100.3 | 99.1 | 98% | 99% |
| Melanoma/carcinoma | 77 | 30 (39%) | 4 (5%) | 2 (3%) | 79.7 | 78.3 | 97% | 98% |
| Other/unspecified cancer | 23 | 18 (78%) | 1 (4%) | 1 (4%) | 26.6 | 26.6 | 86% | 86% |
| Stratified | 3004.9 | 2996.9 | 99% | 100% | ||||
| Known to have died? | P(het)=0.029 | P(het)<0.001 | P(het)=0.005 | |||||
| No | 2332 | 173 (7%) | 194 (8%) | 103 (4%) | 2349.1 | 2340.7 | 99% | 100% |
| Yes | 653 | 33 (5%) | 30 (5%) | 14 (2%) | 654.7 | 653.8 | 100% | 100% |
| Stratified | 3003.8 | 2994.4 | 99% | 100% | ||||
Abbreviations: A=all late CR notifications were feedback; B=none was; CCLG=Children's Cancer and Leukaemia Group; CNS=intracranial and intraspinal (central nervous system); CR=general cancer registry; P(het)=result of test for heterogeneity between categories.