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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Expert Rev Proteomics. 2010 Dec;7(6):833–848. doi: 10.1586/epr.10.88

Figure 2. Representative SELDI-TOF MS spectra from plasma from patients with sickle cell disease with and without pulmonary hypertension.

Figure 2

The vertical axes represent intensity of peaks in arbitrary units, and the horizontal axes represent mass:charge ratio (m/z). These four spectra were obtained from plasma eluted from anion exchange resin, bound to IMAC30–Cu2+ matrix, and ionized by SELDI-TOF MS. Two specimens are from sickle cell disease (SCD) patients without pulmonary arterial hypertension (A & B) and two are from SCD patients with PAH (C & D). A peak at m/z 28.1 kDa was observed at lower average intensity in SCD patients with PAH (arrows). IMAC: Immobilized metal-affinity capture; PAH: Pulmonary arterial hypertension. Reproduced with permission from [56].