Table 4.

Differences in cortical thickness between the NC–MCI, MCI–AD and NC–AD groups computed with the proposed method.

Structure	NC vs. MCI			MCI vs. AD			NC vs. AD
	Difference (mm)	p-Value	%Atrophy	Difference (mm)	p-Value	%Atrophy	Difference (mm)	p-Value	%Atrophy
Hipp L	0.566	<0.001	17.67*	0.200	0.198	7.59	0.766	<0.001	23.92*
Hipp R	0.432	<0.001	14.25*	0.308	0.019	11.83	0.740	<0.001	24.40*
Ang L	0.292	<0.001	10.36*	0.127	0.318	5.03	0.420	<0.001	14.87*
Ang R	0.244	0.002	9.19	0.106	0.325	4.40	0.351	<0.001	13.18*
STG L	0.247	<0.001	9.68*	0.056	0.490	2.41	0.302	<0.001	11.85*
STG R	0.254	<0.001	9.49*	0.062	0.424	2.56	0.315	<0.001	11.81*
ITG L	0.323	0.002	8.57	0.174	0.174	5.05	0.497	<0.001	13.18
ITG R	0.305	<0.001	8.16	0.180	0.192	5.25	0.486	<0.001	12.99
PHG L	0.298	<0.001	7.98	0.172	0.101	5.02	0.470	<0.001	12.59*
PHG R	0.236	0.002	6.25	0.344	0.001	9.72	0.580	<0.001	15.37*
MTG L	0.283	<0.001	9.27*	0.080	0.452	2.89	0.364	<0.001	11.89*
MTG R	0.237	0.005	7.57	0.128	0.283	4.44	0.365	<0.001	11.68*

Hipp, Hippocampus; PHG, Parahippocampal gyrus; ITG, Inferior temporal gyrus; MTG, Middle temporal gyrus; STG, Superior temporal gyrus; Ang, Angular. The star sign (*), indicates significantly atrophied regions, using a FDR-corrected p < 0.05.