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. 2008 Jan;2(1):15–25.

Table 2. Protective index (PI) values of sodium valproate and Nigella sativa seed constituents against MES- PTZ-induced convulsions.

Treatment SVP AE FO VO TQ (CMC) AP PC
PTZ model
PI = TD50/ED50
1.13 0.48 < 0.22 0.81 0.95 < 0.39 0.93
MES model
PI = TD50/ED50
1.07 _ _ 0.43 _ _ 0.34

SVP = Sodium valproate, AE = Aqueous extract, FO = Fixed oil, VO = Volatile oil, TQ = Thymoquinone, AP = α-pinene, PC = p-cymene.