Table (5).
Laboratory Data | METAVIR (activity) (A) | METAVIR (staging) (F) | ||
---|---|---|---|---|
r | p | r | p | |
FBG | 0.80 | 0.01** | 0.43 | 0.02* |
FI | 0.38 | 0.1* | 0.60 | 0.01** |
HOMA-IR | 0.49 | 0.02* | 0.66 | 0.01** |
PCR | 0.41 | 0.031* | 0.32 | 0.22 |
ALT | 0.42 | 0.04* | 0.40 | 0.04* |
PT | 0.87 | 0.01** | 0.49 | 0.01** |
In CHC patients with normal liver enzymes; FBG & HOMA-IR were correlated with METAVIR activity and liver fibrosis scores in table (6) & figure (4) (p=0.04, 0.01 and p=0.01, 0.02 respectively) while viral load (PCR) was correlated with METAVIR activity score only (p=0.031) and prothrombin time was correlated with METAVIR fibrosis score (p=0.02). There is a correlation between serum fasting insulin and liver fibrosis progression in CHC patients with elevated enzymes (p=0.01) table (5) and in those with normal enzymes (p=0.02) (table-6).