Table 5.

Risk of LOAD Based on Risk Score Categories

Risk Score	No. at Risk	Cases, No. (%)	HR (95% CI)	P Value
Probable and Possible LOAD (n=92)
0–14	315	7 (2.2)	1 [Reference]
15–18	225	13 (5.8)	3.74 (1.42–9.88)	.008
19–22	193	11 (5.7)	3.55 (1.31–9.62)	.01
23–28	187	33 (17.6)	12.57 (5.26–30.08)	<.001
>28	131	28 (21.4)	20.47 (8.38–49.99)	<.001
P value for trend				<.001
Probable LOAD (n=80)
0–16	250	1 (0.4)	1 [Reference]
17–21	189	7 (3.7)	3.381 (0.87–13.13)	.07
22–26	222	7 (3.2)	4.98 (1.36–18.19)	.01
27–32	184	15 (8.2)	14.01 (4.06–48.39)	<.001
>32	206	35 (17.0)	35.81 (10.81–118.61)	<.001
P value for trend				<.001

Abbreviations: CI, confidence interval; HR, hazard ratio; LOAD, late-onset Alzheimer disease.