Table 2.

Incidence of Early and Late Age-Related Macular Degeneration (AMD) in White Women in the Study of Osteoporotic Fractures.

Age Group	Number of Women at Risk	Incidence N (%)	95% CI of Incidence	Weighted Incidence* (95% CI)
Early AMD
Age (years)
74–79†	724	158 (21.8%)	18.9–25.0	21.9 (18.8–25.0)
80–84	271	90 (33.2%)	27.6–39.2	33.2 (27.6–38.7)
85+	38	11 (28.9%)	15.4–45.9	29.0 (14.8–43.1)
Total	1033	259 (25.1%)	22.5–27.8	25.3 (22.6–28.0)
Trend p-value‡		0.0007		0.0009
Late AMD
Age (years)
74–79†	991	41 (4.1%)	3.0–5.6	4.3 (3.0–5.6)
80–84	426	40 (9.4%)	6.8–12.6	9.4 (6.7–12.2)
85+	76	11 (14.5%)	7.5–24.4	14.5 (6.7–22.3)
Total	1493	92 (6.2%)	5.0–7.5	6.4 (5.1–7.6)
Trend p-value‡		<0.0001		<0.0001

AMD=Age-related macular degeneration; CI=Confidence interval.

^*Estimates were weighted by attrition weights.

^†Includes 14 subjects at risk for incident early AMD who were 74 years old and four (28.6%) of them had incident early AMD, and 22 subjects at risk for incident late AMD who were 74 years old and one (4.5%) of them had incident late AMD.

^‡Cochran-Armitage trend test.