Table 5.
Risk factors for incident Age-Related Macular Degeneration (AMD) in the Study of Osteoporotic Fractures Eye Study.*
Risk Factor | Unadjusted | Age-adjusted | Age and Race-adjusted | Multivariable-adjusted† |
---|---|---|---|---|
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
Early AMD | ||||
Any alcohol in last 30 days: Yes vs. No | 1.67 (1.27–2.19) | 1.58 (1.20–2.09) | 1.58 (1.20–2.08) | 1.57 (1.18–2.11) |
Current smoker: Yes vs. No | 0.99 (0.48–2.04) | 1.13 (0.54–2.35) | 1.13 (0.55–2.36) | 1.11 (0.53–2.35) |
Late AMD | ||||
Any alcohol in last 30 days: Yes vs. No | 0.86 (0.57–1.31) | 0.79 (0.52–1.21) | 0.75 (0.49–1.15) | 0.79 (0.51–1.23) |
Current smoker: Yes vs. No | 0.79 (0.24–2.58) | 0.99 (0.30–3.25) | 1.01 (0.31–3.33) | 1.04 (0.31–3.47) |
AMD=Age-related macular degeneration; OR=Odds ratio; CI = Confidence interval.
Estimates were weighted by attrition weights.
Model includes alcohol consumption, current smoking, age, race, hypertension, walks for exercise, and study sites.