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. 2011 Jan 6;3(1):57–64.

Figure 1.

Figure 1

Dose-response effect of Rosuvastatin on neuronal survival in cortical neurons exposed to OGD and OGD/reoxygenation. A. Cortical neurons were pre-treated for 24 hrs with RSV at concentrations of 10 nM, 100 nM and 1 μM in culture medium and then exposed to 3 hrs OGD in the presence of RSV. B. Cortical neurons were pre-treated with RSV for 24 hrs and then exposed to OGD followed by 24 hrs reoxygenation in the continuos presence of RSV. At the end of the treatments mitochondrial oxidative capacity was evaluated by MTT assay. Data are expressed as a percentage ± SEM vs. control untreated cells *P<0.05 vs. its respective control group; **P<0.05 vs OGD or OGD/Rx groups. CTL=Control, OGD=Oxygen and Glucose Deprivation, Rx = reoxygenation.