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. 2011 Mar 31;6(3):e18207. doi: 10.1371/journal.pone.0018207

Figure 1. HGN194 targets a unique conformational V3-loop epitope.

Figure 1

Plasma from monkey RMf-9 (white bars with black dots), chronically infected with SHIV-1157ip, was used as positive control as well as 2G12 (grey bars), a mAb targeting a conformational mannose-dependent epitope on gp120. Herceptin (white bars) and plasma from naïve monkey RMj-2 (striped bars) were used as negative controls. Results of conformational ELISA are shown. Additional control studies have been published earlier [24].